Evert J Homan Selected Research

Methylenetetrahydrofolate Dehydrogenase (NADP) (Dehydrogenase, Methylenetetrahydrofolate)

1/2022	Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress.
1/2022	The First Structure of Human MTHFD2L and Its Implications for the Development of Isoform-Selective Inhibitors.

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Evert J Homan Research Topics

Disease

4	Neoplasms (Cancer) 01/2022 - 04/2014
1	Genomic Instability 01/2022
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2022
1	Infections 12/2021
1	Leukemia 10/2020
1	Inflammation (Inflammations) 11/2018

Drug/Important Bio-Agent (IBA)

3	Reactive Oxygen Species (Oxygen Radicals)IBA 12/2020 - 04/2014
2	Methylenetetrahydrofolate Dehydrogenase (NADP) (Dehydrogenase, Methylenetetrahydrofolate)IBA 01/2022 - 01/2022
2	Pharmaceutical PreparationsIBA 01/2022 - 01/2022
2	EnzymesIBA 01/2022 - 01/2022
2	DNA (Deoxyribonucleic Acid)IBA 11/2018 - 04/2014
1	ThymidineIBA 01/2022
1	Proteins (Proteins, Gene)FDA Link 01/2022
1	Folic Acid (Vitamin M)FDA LinkGeneric 01/2022
1	Ganciclovir (Cytovene)FDA LinkGeneric 12/2021
1	Small Interfering RNA (siRNA)IBA 12/2020
1	2-mercaptopurineIBA 10/2020
1	Nudix HydrolasesIBA 10/2020
1	NucleotidesIBA 10/2020
1	DNA Glycosylases (DNA Glycosylase)IBA 11/2018
1	7,8-dihydro-8-oxoguanineIBA 11/2018
1	8-hydroxyguanineIBA 11/2018

Therapy/Procedure

1	Therapeutics 12/2021